畜牧兽医学报 ›› 2013, Vol. 44 ›› Issue (6): 829-836.doi: 10.11843/j.issn.0366-6964.2013.06.001

• 综述 •    下一篇

Ghrelin基因衍生肽Des-acyl ghrelin和Obestatin主要功能及其分泌调节

耿春银1,2,杨连玉3,严昌国2,任丽萍1,周振明1,孟庆翔1*   

  1. (1. 中国农业大学动物科技学院 动物营养学国家重点实验室,北京 100193; 2. 延边大学农学院,延吉 133000;3. 吉林农业大学动物科技学院,长春 130000)
  • 收稿日期:2012-11-08 出版日期:2013-06-23 发布日期:2013-06-23
  • 通讯作者: 孟庆翔,教授,博士生导师,主要从事反刍动物营养与饲料科学研究,E-mail: qxmeng@cau.edu.cn
  • 作者简介:耿春银(1980-),男,吉林榆树人,博士生,主要从事动物营养与饲料科学研究,E-mail: cygeng1011@163.com
  • 基金资助:

    国家肉牛牦牛产业技术体系项目(CARS-38);吉林省教育厅“十二五”科学技术研究项目(2012052)

The Main Function and Secretion Regulation of Des-acyl Ghrelin and Obestatin Derived from Ghrelin Gene

GENG Chun-yin1, 2, YANG Lian-yu3, YAN Chang-guo2, REN Li-ping1,ZHOU Zhen-ming1, MENG Qing-xiang1*   

  1. (1. State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China; 2. Agricultural College of Yanbian University,Yanji 133000,China; 3. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130000, China)
  • Received:2012-11-08 Online:2013-06-23 Published:2013-06-23

摘要:

 除胃饥饿素(Ghrelin)外,Ghrelin基因还能衍生出多种具有活性的产物。本文对Ghrelin基因衍生肽进行了介绍,并对2种主要的产物去酰化胃饥饿素(Des-acyl ghrelin)和肥胖抑制素(Obestatin)的分布、主要功能及其分泌调节等内容进行了综述,旨在为开展其在动物生产领域中的研究提供理论基础。

Abstract:

Ghrelin gene can generate various bioactive molecules besides Ghrelin. In this review, not only the Ghrelin derived peptide were introduced, but the physiological functions, distributions and the factors which affect secretion of Des-acyl ghrelin and Obestatin were reviewed. This paper aimed to provide theoretical basis for future researches on Des-acyl ghrelin and Obestatin in the field of animal production.

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